@BrunerLab

Chemical Biology Research at UF Biosynthesis | Crystallography | Mechanistic Enzymology | Organic Chemistry Group-run account

 Gainesville, FL
brunerlab.com/
Joined February 2019
  • Tweets62
  • Following69
  • Followers164
Save the Date! UF Chemistry-Biology Interface Mini Symposium on Nov 9, 2024. Join us for a day of research and networking!
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🚀 It’s OFFICIAL! 🎉 ACS-ORCA is now a General Registered Student Organization @UFChemistry ! We’re excited to launch the graduate student club this fall semester. Get ready for a year of chemistry fun and career development! 🧪🔬 #UF #OrganicChemistry #GradStudentLife
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New Preprint from our lab. The @BrunerLab and us developed yeast strains to perform functional genomics studies of the signal recognition particle. We were surprised strains with titratable expressions of the SRP complex did not exist, so we built some. biorxiv.org/content/10.1101/…

A scalable genetic tool for the functional analysis of the signal recognition particle

Mutations in the SRP54 gene are linked to the pathophysiology of severe congenital neutropenia (SCN). SRP54 is a key protein comprising one of the six protein subunits of the signal recognition...

biorxiv.org
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Bruner Lab retweeted
YDing_UF@UfYding10 Feb 2024
Excited to unveil the first insights into dolastatin 10 biosynthesis. Thanks to all authors, the Luesch, Paul, @BrunerLab labs, and RM1 and R35 @NIGMS. Biosynthesis of Dolastatin 10 in Marine Cyanobacteria, a Prototype for Multiple Approved Cancer Drugs pubs.acs.org/doi/10.1021/acs…

Biosynthesis of Dolastatin 10 in Marine Cyanobacteria, a Prototype for Multiple Approved Cancer...

Abstract. Dolastatin 10, a potent tubulin-targeting marine anticancer natural product, provided the basis for the development of six FDA-approved antibody–

pubs.acs.org
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we are looking for a #compchem postdoc to work on an NIH funded project to characterize BET proteins, the complexes it forms, and identifying new viral and host PPIs. Someone with expertise in MD, python, ML, and a passion to solve biological puzzles is a great fit! Pls RT
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There is a postdoc opening in the Butcher Lab at the University of Florida! Come join us to discover novel nematode natural products and to uncover their role in chemical signaling. Begins ASAP. For more info, see: butcher.chem.ufl.edu/our-gro… Please Retweet! #postdocjobs
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Bruner Lab retweeted
Jarrod Mousa@jjmousa14 Mar 2023
We are seeking to hire 2-3 postdoctoral fellows! Please retweet!
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Congrats to Steven Bruner, Ph.D., of @UFChemistry & @CarlDenard, who have received a grant from @LiveLikeBella to research detrimental mutations in the human SRP54 gene that cause inherited bone marrow failure syndromes & progression of pediatric #cancers: go.ufl.edu/b8ycfz2
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🔥 New advance article for RSC Chemical Biology! 🔥 @UfYding, @BrunerLab et al @UF exploring the metabolism of nitroimidazole drug molecules by a #nitroreductase from human #pathogen Haemophilus influenzae 🤓 #chembio 🧐Read the #OpenAccess article 👉ow.ly/nfRn50IbHyX
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Our issue this week includes work by Takashi Fujishiro, Yasuhiro Takahashi, @chemzymes, @BreakingBiochem, Wilfred A. van der Donk, Friedrich Hammerschmidt, Ahmad Galaleldeen, Robert S. Phillips, @BrunerLab and more. Check out issue 20 now at pubs.acs.org/toc/bichaw/60/2…
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Bruner Lab retweeted
YDing_UF@UfYding25 Aug 2020
Replying to @UFPharmacy
Thanks for developing this news release! I also want to express my sincere appreciation to @BrunerLab who has long supported our studies.
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Bruner Lab retweeted
YDing_UF@UfYding21 Aug 2020
Very pleased that our recent work on cyanobacterial dihydroxyacid dehydratase is featured as a cover art by ACS Chemical Biology | Vol 15, No 8 pubs.acs.org/toc/acbcct/15/8… Congrats to our artists Brain, @BrunerLab and other team members.
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Bruner Lab retweeted
YDing_UF@UfYding29 Jul 2020
Congrats to Peilan Zhang, Brian MacTavish, and other coworkers @BrunerLab @UfYding Their six-year hard work has paid off @ChemicalBiology Cyanobacterial Dihydroxyacid Dehydratases Are a Promising Growth Inhibition Target pubs.acs.org/doi/10.1021/acs…

Cyanobacterial Dihydroxyacid Dehydratases Are a Promising Growth Inhibition Target

Abstract. Microbes are essential to the global ecosystem, but undesirable microbial growth causes issues ranging from food spoilage and infectious diseases

pubs.acs.org
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Metabolite damage and repair in metabolic engineering design. - PubMed - NCBI ncbi.nlm.nih.gov/pubmed/2903…
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