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Nancy

@NancyArthurPhD

Postdoc @WashUHeme . Cancer researcher,wife & mom. Always seeking to make a difference in the fight against cancer. Livin each day with joy&purpose.

 St Louis, MO
Joined December 2019
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  • Followers392
The most important briefings of the day. Karl Deisseroth, professor of bioengineering and of psychiatry and behavioral sciences, shares the news of his Nobel Prize with his kids.
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BREAKING NEWS The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
Image from The Nobel Prize (@NobelPrize)
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In 2025, Keytruda (pembrolizumab) was the number one drug for global sales ~$32 billion, targeting PD-1, for cancer immunotherapy. But we didn't know precisely how it works until today @ScienceMagazine science.org/doi/10.1126/scie… science.org/doi/10.1126/scie…
Image from Eric Topol (@EricTopol)
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I don’t post much anymore but thought I would take a moment to share my feelings on an issue that has been papered over by the negative impact that external forces have had on science and scientists: the toxicity of our own interactions within the scientific community. (1/10)
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Pre-existing cell states predict resistance to multiple treatments dlvr.it/TRn0Zw
Pre-existing cell states predict resistance to multiple treatments

Pre-existing cell states predict resistance to multiple treatments

Schaff et al. use multi-treatment clonal tracing with single-cell RNA sequencing to show that rare melanoma clones resist multiple treatments through pre-existing gene expression states. They...

cell.com
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Nancy retweeted
Cell (@CellCellPress) profile picture
Cell@CellCellPressJan 23
Now online! MYC binding to nascent RNA suppresses innate immune signaling by R-loop-derived RNA-DNA hybrids dlvr.it/TQWcrR
MYC binding to nascent RNA suppresses innate immune signaling by R-loop-derived RNA-DNA hybrids

MYC binding to nascent RNA suppresses innate immune signaling by R-loop-derived RNA-DNA hybrids

RNA-binding-mediated multimerization of MYC concentrates RNA-degrading factors around double-stranded RNAs and R-loops. This prevents aberrant RNAs from accumulating and leaking into the cytosol....

cell.com
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Congratulations to Nancy Arthur, our January #CGCVolunteerSspotlight! 👏 As a CGC trainee volunteer and Communications Committee member, Nancy plays a vital role in our community. Learn more about her here: buff.ly/B0VIrFG #CGCVolunteers #genomics #cancer #research
Image from Cancer Genomics Consortium (CGC) (@CG_Consortium)
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2025 Update on MRD in Acute Myeloid Leukemia: A Consensus Document from the ELN-DAVID MRD Working Party ashpublications.org/blood/ar…
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🚨 This is it people … you heard it first at #ASH25 🚨 ELN #MRD 205 guidelines are in press in @BloodPortfolio Bad news: It’s more complicated than before… 🤯 Good news: there’s an app for it 😉 eln-aml-mrd-2025.vercel.app/
Image from Sanam Loghavi, MD صنم لغوی 🔬🧬 (@sanamloghavi)
Image from Sanam Loghavi, MD صنم لغوی 🔬🧬 (@sanamloghavi)
Image from Sanam Loghavi, MD صنم لغوی 🔬🧬 (@sanamloghavi)
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The scariest thing in academia 😅
Image from Keith Siau (@drkeithsiau)
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New preprint! We know cancer cells with somatic mutations are selected to evade the immune system. With @imartincorena Peter Campbell @ZJL1435957 @QuotientTx, we asked if immune cells with somatic mutations are also selected to fight cancer. biorxiv.org/content/10.1101/… 1/5
Somatic TYK2 activating mutations in tumor-infiltrating T cells promote anti-cancer immunity

Somatic TYK2 activating mutations in tumor-infiltrating T cells promote anti-cancer immunity

Cancer cells evolve to increase fitness and evade the immune system, but it is not clear if tumor infiltrating lymphocytes (TILs) undergo selection for somatic mutations that augment anti-cancer...

biorxiv.org
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Rapid epigenomic classification of acute leukemia | Nature Genetics nature.com/articles/s41588-0…
Rapid epigenomic classification of acute leukemia

Rapid epigenomic classification of acute leukemia

Nature Genetics - The authors present a molecular classification of acute leukemia using 5-methylcytosine signatures, together with a neural network-based classifier for clinical use.

nature.com
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"We added the requested experiments and thank the reviewers for their helpful suggestions"
Image from Oded Rechavi (@OdedRechavi)
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Congratulations @OffCMCVellore on retaining #NIRF ranking as 3rd best Medical College in India. @dpradhanbjp Benchmarks help but staying true to the call to "Not to be ministered unto, but to minister" will define who we really are meant to be. Three cheers to the Silver & Blue
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We mourn the loss of Dr. Stuart Kornfeld - an incredible teacher & mentor. He was an outstanding role model & leader, fostering research training, mentorship & scientific success for generations of trainees. Dr. Kornfeld was known for providing lifelong support to his trainees.
Image from WashU Medicine Division of Physician-Scientists (@WashUDPS)
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Nancy retweeted
nature (@Nature) profile picture
nature
@Nature31 Jul 2025
A generative artificial-intelligence tool has designed a synthetic CRISPR system that successfully edits human DNA go.nature.com/3JadkRy
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🌍 Thrilled to announce our International Speaker Lineup for the 5th HCC Annual Meeting! 🩸 Join us Oct 3–5, 2025 at NCI-AIIMS, Jhajjar — where real-world expertise meets meaningful progress in blood cancer care. 🔗 More: hemecancer.org/5th-annual-me… #HCCIndia #Hematology2025
Image from Hematology Cancer Consortium (@HCC_HemeCancer)
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New in @NatureBiotech: a team led by scientists at MSK and @UofT have developed a new platform to facilitate the study of RNA-binding proteins (RBPs) across hundreds of species of plants, insects, and animals. Learn more: go.nature.com/4l3LYtI nature.com/articles/s41587-0…
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The Cancer Genomics Consortium is thrilled to announce the publication of a landmark consensus guideline honed by the CGC’s Plasma Cell Neoplasm Working Group in Blood Cancer Journal. Learn more here: buff.ly/89CuBtz #CGCVolunteers #genomics #cancer #research #genetics
Image from Cancer Genomics Consortium (CGC) (@CG_Consortium)
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As I write pars of my book, it strikes me that so little has been done in the science of science education in India. The impact of allyship in science. The experiences with mentorship. The study of the well-being of PhD scholars. Big gaps to be filled! 🙏🖋️📝
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