UMass Chan Program in Innate Immunity (@UMassChanPII) header
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We are a group of Innate Immunity researchers at UMass Chan Medical School studying immune defenses & inflammation in health and disease.

UMass Chan Medical School
Joined August 2021
Photo by UMass Chan Program in Innate Immunity (@UMassChanPII)Photo by UMass Chan Program in Innate Immunity (@UMassChanPII)Photo by UMass Chan Program in Innate Immunity (@UMassChanPII)Photo by UMass Chan Program in Innate Immunity (@UMassChanPII)Photo by UMass Chan Program in Innate Immunity (@UMassChanPII)Photo by UMass Chan Program in Innate Immunity (@UMassChanPII)Photo by UMass Chan Program in Innate Immunity (@UMassChanPII)Photo by UMass Chan Program in Innate Immunity (@UMassChanPII)Photo by UMass Chan Program in Innate Immunity (@UMassChanPII)Photo by UMass Chan Program in Innate Immunity (@UMassChanPII)
@UMassChanPII @UMass_Medicine faculty and chief of Rheumatology Dr. Roberto Caricchio's work on CAR T cell therapy treatment in lupus nephritis will be featured on @Chronicle5! Be sure to watch his segment Nov 7 at 7:30 ET.
Tune into @Chronicle5 tomorrow to hear from our own Dr. Roberto Caricchio on the topic of CAR T cell treatment in lupus nephritis! #Rheumatology #Lupus
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@UMassChanPII faculty Dr . John Harris @HarrisVitiligo will present Medical Grand Rounds today @UMassChan! We hope to see members of our UMass Chan/UMMH community there! #vitiligo
We invite members of the UMass community to join us today at noon, in person and via Zoom, for our Medical Grand Rounds titled, "Vitiligo Treatment from the Iron Age to the Age of Biologics: New Hope for an Ancient Disease," featuring Dr. John Harris. We hope to see you there!
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UMass Chan Program in Innate Immunity retweeted
Drs. Mingqi Dong (@Mingqi7up) & @FitzgeraldKate from @UMassChan summarize the fundamentals of DNA-sensing pathways and the intricate regulatory networks that keep these pathways in check. ✔️ 📖 Read more in their review: go.nature.com/4eY2Orf
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Congratulations Dr. Ambros @UMassChan! A momentous day indeed! #NobelPrize
UMass Chan Medical School researcher Victor R. Ambros, PhD, shares the 2024 @NobelPrize in Physiology or Medicine for his co-discovery of microRNA, single-stranded RNA molecules that play a critical role in post-transcriptional gene regulation: direc.to/mmJ6 #NobelPrize
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UMass Chan Program in Innate Immunity retweeted
nature.com/articles/s41590-0… I hope this is a helpful review! Appreciate the opportunity to co-write this review in @NatImmunol with my mentor @FitzgeraldKate. Thanks to all the reviewers' comments which significantly elevated our work and thanks to the unsung artists for their art!
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UMass Chan Program in Innate Immunity retweeted
Fantastic news - congratulations to Victor Ambros @UMassChan and Gary Ruvkun @MGH
Victor R. Ambros, PhD, @UMassChan's Silverman Chair in Natural Sciences and professor of molecular medicine, has won a Nobel Prize. Media: Email [email protected] for news conference info and interview requests. #NobelPrize #BreakingNews #AdvancingTogether
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We can't wait to welcome you to @UMassChanPII @UMass_Medicine in November @karthik_varanas!
We are super excited to be welcoming @karthik_varanas to the Division of INnate Immunity @UMassChan this November to start his lab @UMassChanPII ---welcome to @UMassChan @UMassChanGSBS #newPI
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UMass Chan Program in Innate Immunity retweeted
Two new papers from the @RPWLab @umass_medicine "reveal broad implications for understanding pathogen detection in higher animals and evolutionary origins of immunity". Read the story below in @UMassChan news.
The 2 papers began with 1 question: “What regulates the immune response in C. elegans?” The studies reveal broad implications for understanding pathogen detection in higher animals and evolutionary origins of immunity itself: umassmed.edu/news/news-archi… @UMassChan @UMass_Medicine
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Congratulations to @UMassChanPII faculty @AtukoralePU and our @UMassChan colleague @Marcus_Ruscetti on their new study published in Science Translational Medicine! Check out their exciting work advancing pancreatic cancer research below.
.@UMassChan scientists @Marcus_Ruscetti @AtukoralePU are making strides in pancreatic cancer research, with a study published in @ScienceTM: brnw.ch/21wN7kH
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UMass Chan Program in Innate Immunity retweeted
Tune into @NBC10Boston at 5:30 p.m. tonight to hear Marcus Ruscetti, PhD, and Prabhani Atukorale, PhD, discuss their promising research in fighting pancreatic cancer. @JeffNBCBoston @UMassAmherst @Marcus_Ruscetti @AtukoralePU
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Congratulations, Jane! 🎉🔬🩺
Last week, I defended my PhD within @UMassDerm and @UMassChanPII ! Thank you to my incredible mentors, Ann Rothstein, Mehdi Rashighi, and Michael @BrehmLab. Any return-to-clinic tips are greatly appreciated 🩺❤️
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Check out this #newpublication and beautiful images from the @FitzgeraldKate and #AnnRothstein labs in @JCI_insight! @UMass_Medicine @UMassChan
An autoinflammatory syndrome-associated STING mutation supports formation of germinal centers containing immunocompetent cells in the lungs of irradiated mice following BMT- insight.jci.org/articles/vie… Study from@ImmunoKevin and colleagues @kchianggg @FitzgeraldKate @UMassChanPII
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Also thrilled to announce the 2024-25 Innate Immunity Training Program trainees! Learn more at umassmed.edu/pii/education-a… @UMass_Medicine @UMassChan #predoctoraltraining #innateimmunity
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Excited to announce the 2024-25 Autoimmunity and Autoinflammation Training Grant trainees! Learn more at umassmed.edu/pii/education-a… @UMass_Medicine @UMassChan #predoctoraltraining #innateimmunity #adaptiveimmunity
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UMass Chan Program in Innate Immunity retweeted
You can read our new study, out now in @JCI_Insight! (tinyurl.com/4bjcraeu) We examine how expression of a STING gain-of-function (GOF) mutation in radioresistant host cells results in the development of lymphocyte autoimmunity. Some highlights from our study: (1/7)
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We thank our speakers, program chairs, organizers, and everyone who attended today's Innate Immunity Day program!
Innate Immunity Day 2024 @UMassChan has kicked off this afternoon with a fantastic line up of talks and a full house in the beautiful New Education and Research Building. 🦠🔬
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Innate Immunity Day 2024 @UMassChan has kicked off this afternoon with a fantastic line up of talks and a full house in the beautiful New Education and Research Building. 🦠🔬
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UMass Chan Program in Innate Immunity retweeted
The Orzalli lab’s first paper is out today @JExpMed! See the excellent tutorial from first author @JustKOS1 below.
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