Neuroscientist - attention - decision-making - large-scale interactions
Hamburg, Deutschland
Joined January 2017
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New paper alert 📣 #Neuroscience
"Rhythmic sampling of multiple decision alternatives in the human brain" @NatureComms
together with Y. Cao, M. Tohidi, @donner_lab & @k_tsetsos
nature.com/articles/s41467-0… 🧵1/
Marcus Siems retweeted
New paper! Theta as a master clock. It couples to relevant spiking, direct information flow and has nested cross-frequency interactions with beta and gamma oscillations.
Theta-based organization of information in the frontal cortex
sciencedirect.com/science/ar…
#neuroscience
Marcus Siems retweeted
1/ We discovered something totally unexpected about the neural structure of consciousness that overturns decades of thinking on its biological basis and brings us significantly closer to the recipe for generating conscious awareness.
New preprint: biorxiv.org/content/10.64898… (led by @HesseJanis, with @FrankLanfranchi, @_conor_mcgrory, @Yuelin_Shi, and @EngelTatiana)
Marcus Siems retweeted
A cautionary comment when applying frequency analyses to single-trial decoding outputs: doi.org/10.1111/ejn.70725
Marcus Siems retweeted
This paper changed my life: A first glimpse into the ‘middle’ of brain processing
thetransmitter.org/this-pape…
#neuroscience
Neuronal power spectra can be described by 3 parameters: intercept, oscillations & aperiodic slope.
Intercept (tDCS) & oscillations (tACS) have been modulated with non-invasive electrical stimulation - but what happens when you try modulate the aperiodic slope?
Q. van Engen, @justinmriddle & B. Voytek find that you can improve working memory performance by steepening the aperiodic slope with tES
Transcranial Random Aperiodic Stimulation Improves Working Memory Precision biorxiv.org/content/10.64898…
Marcus Siems retweeted
The most important briefings of the day.
Karl Deisseroth, professor of bioengineering and of psychiatry and behavioral sciences, shares the news of his Nobel Prize with his kids.
Marcus Siems retweeted
Thanks to everyone sharing in this moment!
I’m so grateful to my trainees & collaborators…
dlab.stanford.edu/group-memb…
(pic: optogenetics conference chairs, Tuscany)
Reading for all those asking:
for technical details: dlab.stanford.edu
for everyone: deisseroth.org/projections
Marcus Siems retweeted
My lab’s microbial-opsin work (and by far most of the field also) is pure basic science, but it was intriguing to review the community's clinical progress– both direct translation as in retinal degeneration, and indirect translation not involving gene therapy– with a wonderful and broad international team of co-authors…
nature.com/articles/s41593-0…
& to adapt a long-ago figure from PMID:28912215 (2017) on the inner workings of light-gated ion channels with my long-time collaborator Peter Hegemann; photo is a memory from that year.
Marcus Siems retweeted
BREAKING NEWS
The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
Marcus Siems retweeted
netneurotools: a trainee-oriented approach to network neuroscience | doi.org/10.1038/s41596-026-0…
Our lab’s internal toolkit for accomplishing everyday tasks in brain imaging @NatureProtocols ⤵️
Marcus Siems retweeted
The New York Times ha finalizado su lista de las mejores series del siglo.
Breaking Bad tomó el primer puesto.
Marcus Siems retweeted
The ITRUSST Practical Guide on Transcranial Ultrasonic Stimulation (TUS) for neuromodulation is finally out, endorsed by the International Federation of Clinical Neurophysiology (IFCN). This is quite the “opus magnum” with 23 beautiful educational figures.
buff.ly/40WtIvy
Marcus Siems retweeted
New paper - Improved detection and spatiotemporal spectral analysis of neural traveling waves biorxiv.org/content/10.64898…
Marcus Siems retweeted
Large-scale neural activity data across wakefulness, sleep, and anesthesia are now open. Includes EEG/EMG, brain states, Ca²⁺ traces, and spikes. Please download and play with the data!
Cell Reports: doi.org/10.1016/j.celrep.202…
Scientific Data: doi.org/10.1038/s41597-026-0…
Marcus Siems retweeted
The brain does not turn up the volume on important sounds. It sharpens their timing. By synchronizing neurons to a shared rhythm, attention to a location makes the signal cleaner, not louder.
biorxiv.org/content/10.64898…
#neuroscience
Marcus Siems retweeted
New paper! Decision-making isn't just picking winners via more neural firing, the brain reorganizing activity patterns into different subspaces, shifting from "one option vs. another" to "chosen vs. rejected"
doi.org/10.1016/j.isci.2026.…
#neuroscience
@MIT_Picower @mitbrainandcog
Marcus Siems retweeted
🌍🧠 OHBM 2029 is headed to Rotterdam!
Mark your calendars for June 24–28, 2029
Discover the story behind OHBM 2029, from the meeting logo to why Rotterdam is the perfect host city.
👉 Read the blog: ohbm-com.com/blog/ohbm-2029-…
Marcus Siems retweeted
🚨 8 months later, this paper found its home at @ScienceMagazine. We came up with a generative brain network model based on game theory and found that the human brain is suboptimal both in terms of wiring cost and communication efficiency. Here's why:
science.org/doi/10.1126/scia…
🚨first postdoc preprint alert 🚨
We use game theory and reservoir computing to show the brain is not optimally wired for communication or wiring economy because of a third pressure in the trade-off: computational reliability.
biorxiv.org/content/10.64898…
Marcus Siems retweeted
The prefrontal cortex sends a theta rhythm signal down to visual cortex to boost relevant stimulus. Suppression of irrelevant stimuli happens visual cortex using its own rhythms to gate when those neurons are allowed to fire.
biorxiv.org/content/10.64898…
#neuroscience
