Instructor at @StanfordMed, interested in statistical & ML methods for scRNA-Seq and RNA splicing @StanfordDBDS @StanfordBiochem
Stanford, CA
Joined July 2012
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Roozbeh Dehghannasiri retweeted
Reference-free discovery with barcoded single-cell sequencing - @SalzmanLab @sdeorowicz go.nature.com/4cqxwLp
Roozbeh Dehghannasiri retweeted
Mouse lemurs are the smallest and fastest-reproducing primates, and now there's an impressive mouse lemur molecular cell atlas
go.nature.com/3H8vaE2
Roozbeh Dehghannasiri retweeted
Nature research paper: Mouse lemur cell atlas informs primate genes, physiology and disease
go.nature.com/3Hd7fDj
Roozbeh Dehghannasiri retweeted
BREAKING NEWS
The Norwegian Nobel Committee has decided to award the 2023 #NobelPeacePrize to Narges Mohammadi for her fight against the oppression of women in Iran and her fight to promote human rights and freedom for all.
#NobelPrize
Roozbeh Dehghannasiri retweeted
Our August issue is live! 🎉
nature.com/nmeth/volumes/20/…
On the cover, a benchmarking study assessed 16 bioinformatics tools for their abilities to capture true-positive and false-positive circular RNAs.
Cover by @DrawImpacts.
Roozbeh Dehghannasiri retweeted
A large-scale study from @jvdesomp and colleagues benchmarks computational tools for circRNA detection, as well as provides a resource of 315,000 unique putative circRNAs detected in 3 human cell types.
nature.com/articles/s41592-0…
Roozbeh Dehghannasiri retweeted
The Women of Iran are TIME's 2022 Heroes of the Year #TIMEPOY ti.me/3UEjJEE
Roozbeh Dehghannasiri retweeted
ReadZS, from @ea_meyer, Chaung, @roozbehdn & Salzman, for identifying RNA processing (splicing, alternative polyadenylation etc) in RNA-seq data, without the need for pre-existing annotations. It works on both 3'-enriched and non-enriched data genomebiology.biomedcentral.…
ALT Schematic of how the method counts reads from each cell into windows
Roozbeh Dehghannasiri retweeted
Congratulations to everyone involved in four highly collaborative multi-tissue @HumanCellAtlas studies in @ScienceMagazine today, which bring the HCA goal of mapping every cell type in the human body a milestone step closer.
humancellatlas.org/multi-tis…
Roozbeh Dehghannasiri retweeted
Out today in @ScienceMagazine, the Tabula Sapiens is 1 of 4 new open-access cross-tissue human cell atlases. This is a major milestone for #singlecell biology, giving us a deeper understanding of the human body and the diseases that afflict it. bit.ly/3FFbMsZ
Roozbeh Dehghannasiri retweeted
Researchers with the #HumanCellAtlas consortium report a major feat: the creation of detailed maps of more than a million individual cells across 33 organs, representing the most comprehensive, cross-tissue cell atlases to date.
Learn more in Science. ➡ fcld.ly/23zpp4g
Roozbeh Dehghannasiri retweeted
A big day for life science
The Tabula Sapiens, like a Periodic Table of Human Cells, ~500,000 cells analyzed, 24 tissues / organs @ScienceMagazine
"a broadly useful reference to deeply understand and explore human biology at cellular resolution" science.org/doi/10.1126/scie…
Roozbeh Dehghannasiri retweeted
We are happy to announce the release of the Tabula Sapiens track for the human assembly GRCh38/hg38. This track collection covers ~500,000 cells from a total of 24 human tissues and organs using single-cell RNA-sequencing.
Read more about the release at: bit.ly/3qUv9s5
Roozbeh Dehghannasiri retweeted
🫁 First draft of the @humancellatlas Lung Cell Atlas integrates 14 #SingleCell data sets from the global scientific community, including European Commission @discovAIR_HCA project, @ChanZuckerberg Seed Networks, @czbiohub + more. Read the preprint bit.ly/3KFUmOr
Roozbeh Dehghannasiri retweeted
The Splicing Z Score (SpliZ) provides single-cell level quantification of alternative splicing with improved statistical power. @SalzmanLab @julia_olivieri_ @roozbehdn
nature.com/articles/s41592-0…
Roozbeh Dehghannasiri retweeted
A new preprint announces "Tabula Microcebus," a single-cell transcriptomic atlas of the mouse lemur, an emerging primate model organism. Tabula Microcebus contains data on 226,000 cells from 27 organs.🧵 1/7
bit.ly/3HzNh07
Roozbeh Dehghannasiri retweeted
Tabula Microcebus: A transcriptomic cell atlas of mouse lemur, an emerging primate model organism biorxiv.org/cgi/content/shor… #bioRxiv
Roozbeh Dehghannasiri retweeted
Very excited that our paper on the SICILIAN pipeline for robustly identifying splice junctions from scRNA-Seq led by @roozbehdn and @julia_eve_olivieri_ is out in @GenomeBiology! genomebiology.biomedcentral.…
Roozbeh Dehghannasiri retweeted
SICILIAN: single-cell precise splice estimation, from @roozbehdn, @julia_olivieri_, Damljanovic and Salzman. Precise splice junction calls are hard in scRNA-seq; SICILIAN assigns statistical confidence to junctions, increasing agreement between replicates genomebiology.biomedcentral.…
Roozbeh Dehghannasiri retweeted
A significant milestone for the Tabula Sapiens Consortium! The first major publication for this project, on @biorxiv today, details a single-cell transcriptomic atlas of nearly 500,000 cells from 24 different human tissues & organs across 14 donors. (1/6) biorxiv.org/content/10.1101/…
